In this work, two Cu(II) complexes containing 5-amino-1-R-1H-benzimidazol-4-yl)(4-chloro)phenylmethanone hydrazones ligands were synthesized and their spectral characterization, DFT calculations, and catalytic activity were reported. New heterocyclic hydrazone ligands were prepared by the reaction of o-amino-ketones with hydrazine hydrate in high yield. Structural assignments of new compounds were based on their microanalytical and spectral data and formula [Cu(L)2(H2O)2](SO4) was suggested for complexes. Moreover, to gain a further insight into the geometry of synthesized complexes, the DFT calculations were carried out at the B3LYP/6-311+G(d,p) level of theory. The catalytic activity of Cu(II) complexes as heterogeneous catalysts were also investigated in the synthesis of biologically active compound 3,4-dihydropyrimidin-2(1H)-one C5 ester, via classical Biginelli reaction followed by trans-esterification reaction. The results confirmed that the current method formed the products at the lower reaction time and high yields, which might as a result of the enhanced reactivity of the reactants on the surface sites of Cu(II) complexes.
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Ghamati, Z., Pordel, M., Davoodnia, A., & Beyramabadi, S. A. (2022). Synthesis, DFT calculations and catalytic activity in the Biginelli reaction of two hydrazone Cu(II) complexes. Inorganic Chemistry Research, 6(1), 69-75. doi: 10.22036/icr.2022.336558.1127
MLA
Zahra Ghamati; Mehdi Pordel; Abolghasem Davoodnia; S. Ali Beyramabadi. "Synthesis, DFT calculations and catalytic activity in the Biginelli reaction of two hydrazone Cu(II) complexes". Inorganic Chemistry Research, 6, 1, 2022, 69-75. doi: 10.22036/icr.2022.336558.1127
HARVARD
Ghamati, Z., Pordel, M., Davoodnia, A., Beyramabadi, S. A. (2022). 'Synthesis, DFT calculations and catalytic activity in the Biginelli reaction of two hydrazone Cu(II) complexes', Inorganic Chemistry Research, 6(1), pp. 69-75. doi: 10.22036/icr.2022.336558.1127
VANCOUVER
Ghamati, Z., Pordel, M., Davoodnia, A., Beyramabadi, S. A. Synthesis, DFT calculations and catalytic activity in the Biginelli reaction of two hydrazone Cu(II) complexes. Inorganic Chemistry Research, 2022; 6(1): 69-75. doi: 10.22036/icr.2022.336558.1127