@article { author = {Mardani, Hamid and Forouzani, Mehdi and Geraeeli Moradi, Sara}, title = {Comparative study on the effect of transition metal (Zn2+) and alkaline earth metal (Mg2+) ions on adsorption-release of diclofenac and ibuprofen on nano M-Al-LDH as drug carriers}, journal = {Inorganic Chemistry Research}, volume = {5}, number = {2}, pages = {207-214}, year = {2021}, publisher = {Iranian Chemical Society}, issn = {2538-1865}, eissn = {2538-1865}, doi = {10.22036/icr.2021.282596.1106}, abstract = {In this project, three nanoscale M-Al LDHs, which M is a divalent metal (Mg2+, Zn2+ and/or a mixture of them and LDH = Layered Double Hydroxide) were synthesized by co-precipitation and characterized by general techniques, such as FTIR, XRD, FESEM, and EDS. LDHs have got different physical properties, such as; crystal size, lattice parameters, morphology and drug delivery. These M-Al LDHs were used as drug carriers for diclofenac and ibuprofen, which adsorption and release percentages of drugs by them were studied and compared. The results showed that Al-LDHs including transition metal (Zn2+) are suitable for drug delivery purposes. As the mixed divalent (Zn/Mg)-Al LDHs are more efficient drug carriers for both diclofenac and ibuprofen drugs.}, keywords = {nanomaterial,Drug Delivery,Diclofenac,Layered double hydroxides,Transition Metal}, url = {https://www.inorgchemres.org/article_135368.html}, eprint = {https://www.inorgchemres.org/article_135368_6c9f3d4e6155052cb8df638bfb515123.pdf} }